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The Pokémon-Amie reaction glitch is a glitch in Generation VI.
This glitch occurs when the player plays with a Pokémon in Pokémon-Amie for the first time.
In normal circumstances, there are different reactions for the Pokémon depending on whether it is petted in a 'liked' or 'disliked' spot. The glitch causes the reactions to be the same, except for differences in the 'rubbing' sound effect.