On the other hand, it can be said that power corrupts. The 'wiser' or the more ideological people become, the more they may develop a blind spot. It doesn't mean those highest in power are not correct, but it doesn't mean they have the right to play God either. Whereas Ghetsis could be seen as ideological, N battled with himself to make truth; 'a formula that would change the world'; to make sense of why both people love Pokémon but they are allowed to fight. This could be seen as a coverted form of love.
Colress: So if Ghetsis symbolises yang and N yin, Colress also could have an essence of wuji. He seeks out the answer to a question "even if one without a conscience". If Team Plasma had won, Colress may have became a villain. But it was the protagonist who won, hence Colress came to believe it ''may'' be friendship between people and Pokémon which draws out their power. However, wuji might not mean lack of energy: was Colress formed by the state of events, or destined (without free will) to become the character he became in Sun/Moon?
Lysandre and Cyrus: Lysandre was not (in my opinion, others may see this differently) stereotypically bad from the beginning as he wanted a beautiful world. But it feels the symbolism was: just because you find something beautiful, doesn't necessarily mean it is. Lysandre feared the loss of beauty in the world and wanted to eliminate everyone else. Yet on one hand, it is our differences that makes us all the same (Xerneas). On the other hand ego creates destruction, yet paradoxically is not necessarily bad. (Yveltal). I personally see Zygarde as well as symbolism for nature: things materialise or die, and are not necessarily good or evil, but if there is a disturbance in the ecosystem nature rises its 'ugly' head.
The distinction between these two may be, Lysandre valued qualia, Cyrus valued lack of qualia.
Lusamine: I don't know if I have as much as an opinion on this one yet, but I relate with her. Because Lusamine desired the stereotypically 'feminine' concept of possession, and she could originally have been seen as 'motherly', but you have to be careful your possessions (Ultra Beasts) do not possess you or it may inflate your ego, and like Lysandre what you see as 'beautiful' could not be true to everyone else, and you risk alienation from your friends. Lusamine can be compared with the spiritual concept of the moon and also excessive stereotypical femininity. (Lunala)
Guzma: Although Guzma was a stereotypical 'baddy'/'gangster', he maybe unlike Lusamine did not wear a mask, so all of his aggressive traits were not suppressed. Also according to my friend, it was implied he was a victim to abusive parents; so it could be seen it is only natural he was the way he was. He is not necessarily 'bad', and actually helped the player in Ultra Sun/Ultra Moon to confront the Rockets. Team Rocket said Team Skull had no ideals, and Guzma said something like "yes you got me all figured out". But Guzma was more action than talk, so he blocked the Rockets instead of complaining. (he could symbolise excessive stereotypical 'masculinity').